Hello everybody I realized that in the IC2 (upper YAC512) the VSS pin is not physically connected, however when using ratsnest appears connected. I’m not a specialist but how can IC2 work without a ground? Thank you in advance 
I haven’t looked at the Eagle brd file (I can’t even load it), but I can confirm both YAC512 should have VSS connected to ground, and on the OPL3 module itself, they are both connected to the ground plane. Maybe because those chips are mounted on the bottom makes it a bit confusing? i.e. pin 2 (VSS) is one pin up from bottom left corner.
Pin12 (TST2) is not connected. Pin2 is. Like Wilba said, don’t forget its upside down.
I do understand it’s upside down, in my case I have to connect the pin 2 to groud because I’m not making the PCB with ground plane (toner saving 
) and that’s the only commponent (appears to be) is not physically connected to ground line. Thanks for your replies.