Never experienced problems using my midibox with Live.. Check out the midi interface, I’m using a midex 8 and it works perfectly except for a driver or Windows bug which make mios block when no midi ports are opened by software in the interface and I connect the midibox to it
Turns out to be my firewire interface on my motherboard. I’ve tested a pci-firewire card of a collegue and in worked for 6 hour (then i turned it off )
So anyone with problems with their midi-connection dissapearing (in Live 5.0) should try replacing their firewire interface.