When playing with mplab I found myself switching thru some windows everytime I wanted to load the new syx into the PIC. Here a thing or 2 that cut a little bit in the clicking.
For windows users,
You can add following line to the convert.bat
c:\progra~1\midiox\midiox main.syx
(Assuming midiox.exe sits in c:\program files\midiox)
Next you could create a shortcut to convert.bat, assign it a shortcut key (dont work here 
) or put it in the quicklaunch toolbar (XP?)
You could also let the MIDIOX window ‘stay on top’ by clicking some Icon in the toolbar.
This saves already some switching & clicking, perhaps any of you know more or alternatives ? Perhaps inside the Midiox scripting thing ?
Greetz